Yet among the mature we do speak wisdom, though it is not a wisdom of this age or of the rulers of this age, who are doomed to perish. But we speak God’s wisdom, secret and hidden, which God decreed before the ages for our glory. None of the rulers of this age understood this; for if they had, they would not have crucified the Lord of glory. But, as it is written,‘What no eye has seen, nor ear heard, nor the human heart conceived,what God has prepared for those who love him’— these things God has revealed to us through the Spirit; for the Spirit searches everything, even the depths of God. (1Corinthians 2:6-10)

What we can understand of God's reality is demonstrated in the crucifixion and understood through the Spirit.

The quote is Isaiah 64: 4. It is taken from the beginning of a prayer in which the prophet admits to acts of iniquity, recalls the covenant, and asks for mercy. (See Isaiah 64)

It is possible that Paul is recommending the stance taken by Isaiah as the origin of Spiritual wisdom.

This wisdom does not begin in pride, but in humility. Spiritual wisdom recognizes our absolute dependence on God in the past, now, and in the future.

This is the wisdom of clay in the hands of a potter.